Summary of FACES Affiliated Studies

Integration of HIV care and treatment into MCH in Migori District, Kenya (Researchers: Cohen C., Bukusi E., Turan J., Washington S., Marima R., Penner J., Winestone L.)
This study seeks to determine the most effective way to reach and provide pregnant women with accessible, comprehensive, and high quality HIV care and treatment in Migori District, with implications for other sites in Kenya and sub-Saharan Africa. This study utilizes a prospective cluster randomized design. Twelve FACES-affiliated clinics similar in size, population, and services in Migori district, Kenya that provide ANC will be randomly assigned to receive "integrated ANC, PMTCT & HIV services" (intervention arm) or "non-integrated services" (control arm). This study is funded by the U.S. Centers for Disease Control and Prevention (CDC) as a Public Health Evaluation.
Contact: Janet Turan janet.turan@ucsf.edu

Sub-study: Assessing provider satisfaction with integration of HIV care and treatment into MCH in Migori District, Kenya (Researchers: Cohen C., Bukusi E., Winestone L., Turan J., Washington S., Marima R., Penner J.). This study, conducted within the larger integration trial mentioned above, will examine provider perspectives of HIV care and provider job satisfaction in two service models: "integrated ANC, PMTCT, & HIV services" and "non- integrated HIV services" This study is funded by the CDC within the larger aforementioned study.
Contact: Lena Winestone lenawine@stanford.edu

Sub-study: Assessing patient satisfaction with integration of HIV Care and treatment into antenatal care in Migori District, Kenya. (Researchers: Smith R., Cohen C., Bukusi E., Turan J., Washington S.) This proposed study will function within the clinics randomized in the main study and examine patient satisfaction at the integrated and non-integrated clinics. HIV-positive and HIV-negative pregnant women attending ANC at the 12 clinics in Migori District will be asked to complete a questionnaire. This study is funded by the CDC within the larger integration trial mentioned above and through supplemental student scholarship funding.
Contact: Rachel Smith Rachel.smith@ucsf.edu

The demand for family planning services among HIV-infected individuals receiving care and treatment in Nyanza Province (Researchers: Cohen C., Bukusi E., Grossman D., Newmann S., Marima R., Penner J.) This study will help determine how to best meet the family planning needs of HIV- infected women and to provide information for policy makers and program planners that will help them implement high quality services for this population. This study is a cluster-randomized trial comparing the effects of integrating family planning services into HIV care and treatment programs on contraceptive uptake, contraceptive continuation, and unintended pregnancy rates. The study will compare the integration of family planning services into HIV care and treatment versus the standard referral for family planning services outside of HIV care and treatment programs. The study will be conducted in FACES-affiliated clinics in Nyanza Province, Kenya. This study is funded by the CDC as a Public Health Evaluation.
Contact: Dan Grossman dgrossman@ibisreproductivehealth.org
or Sara Newmann Newmanns@obgyn.ucsf.edu

The effects of HIV/AIDS stigma on use of maternity and HIV services by pregnant women in Kenya (Researchers: Turan J., Holzemer W., Cohen C., Bukusi E., Miller S.) This study will examine the effects of different types of HIV/AIDS stigma on use of maternity services and HIV services, among pregnant women in Migori District, Nyanza Province, Kenya through FACES. This is a prospective study among pregnant women using antenatal care clinics in Kenya and will involve structured interviews and data from medical records, as well as qualitative in-depth interviews. This study is funded by the U.S. National Institute of Health.
Contact: Janet Turan janet.turan@ucsf.edu

A prospective cohort study of the effect of highly anti-retroviral therapy (HAART) on the recurrence of surgically treated High-Grade Cervical Intraepithelial neoplasia in HIV-infected women in Kisumu, Kenya (Researchers: Cohen C., Bukusi E., Huchko M., Marima R., Penner J.) This study will assess the effect of Highly Active Antiretroviral Therapy (HAART) on the recurrence of surgically treated High-Grade Cervical Intraephithelial Neoplasia (HGCIN) in HIV-infected women. It is a prospective cohort study of HIV-infected women receiving care at the FACES-supported clinic in Kisumu, Kenya. Women with HGCIN will be followed for two years after their initial surgical excision to determine the effect of HAART on the recurrence of HGCIN after surgical excision.
Contact: Megan Huchko megan.huchko@obgyn.ucsf.edu